Daytona News Journal on Nutronco, Dr. Acs, and PowerOnco

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Nutrition vs Treatment

New Supplement May Be The Answer For Chemo Patients

By Nikki Ross

nikki.ross@news-jrnl.com

06/25/2018

As if chemotherapy isn’t hard enough on its own, patients who undergo this course of cancer treatment also have the added struggle of maintaining a nutritious diet.

Now these patients have access to a nutritional supplement specifically designed to give them the nutrients they need when they find it hard to keep down their meals.

“This is the baby we have been working on for two years,” said Dr. Peter Acs, founder and chief medical officer for Nutronco.

The goal for the supplement, Poweronco, is to improve nutrition, rebuild muscle, support the immune system, decrease inflammation and overall to help with chemotherapy side effects. The product was developed and produced by the emerging nutrition company Nutronco.

“It bothered me to see patients struggle to find a nutritional product that they could keep down,” said Acs, who also is a board-certified hematologist and oncologist.

“I had been wanting to do something like this for years and now it’s here.”

Poweronco is a chocolate flavored powder that chemotherapy patients can mix in six to eight ounces of water once or twice a day.

It costs $99.99 for a one month supply which equals $3.75 per serving. It can be purchased on Nutronco’s website. They are hoping to soon have it available in nutritional stores.

“This is something that they can drink easily because it dissolves nicely in the water,” said Hayes Milani, CFO of Nutronco.

“It’s filling but we also always recommend taking it with a healthy diet.”

Milani and Acs stress that Poweronco is not an alternative treatment though it does help patients tolerate their chemotherapy treatment better then those who don’t take it.

“The main thing for patients undergoing chemotherapy is to eat well and maintaining weighing during treatment,” said Padmaja Sai, hematologist and oncologist at Florida Hospital. “If they are not really getting enough nutrients through their diet then we recommend patients take some nutritional supplements.”

There are several factors that contribute to nutritional deterioration in chemotherapy patients.

The treatment causes cells to stop multiplying in the body, even the good ones.

Patients who undergo chemotherapy may be subject to bed rest and, according to Acs, patients on bed rest lose 10 percent of muscle mass per week.

“Fifty to 80 percent of cancer patients have nutritional issues,” Aces said.

“Forty percent of cancer patients die from malnutrition or cachexia.”

The supplement contains ingredients that help to combat the negative side effects of chemotherapy treatment. It has nucleotides that boost the immune system, help with healing and decreases the chance of infection.

It also contains probiotics that help with the development and stability of the good bacteria in the body, strengthens the immune system and prevents the chemotherapy side effect of diarrhea.

“I don’t see anything wrong with it as long as it ties into everything else we mentioned maintaining a healthy lifestyle, organic diet, no smoking and limited alcohol intake,” Sai said. “As far as I know there is no other nutritional supplement that caters to chemotherapy patients.”

Prebiotics also have been added to the supplement to give good bacteria the surface to grow. Ginger and other ingredients are also there to reduce nausea. It also includes protein. “Many oncologists will be skeptical,” said Dr. Michael Epitropoulos, oncologist, chiropractic and natural medicine physician.

“They have checked for a reaction between the ingredients and the chemotherapy and found that it will not harm treatment like other supplements.”

Acs said his main goal in developing this supplement is to help chemotherapy patients have a more positive outcome. “This is to help them take some control over their nutrition,” Acs said. “And to help them fight against cancer.”

For information on Nutronco and their products, visit nutronco.com.

To contact Dr. Peter Acs, call 352-672-4403.

To contact Hayes Milani, call 352-278-2526.

To contact Dr. Michael Epitropoulos, call 386-274-2520.

Whey Based Supplements

Benefits of Whey-Based Supplements

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Whey-based diets have been linked with prolonged life expectancy and improved physical performance. These observations based on numerous clinical and simulated studies are attributed to diverse biological activities of whey peptides. Whey has been characterized to be excellent nourishment with an array of bioactive components. In fact, it is considered as the richest source of bioactive peptides. Whey protein comprises 20 % of total milk protein and it is rich in branched chain and essential amino acids, functional peptides and immunoglobulins. It confers benefits against a wide range of metabolic diseases such as cardiovascular complications, hypertension, obesity, diabetes, cancer and phenylketonuria. The protein has been validated to boost muscle recovery from resistance exercise-injuries, stimulate gut physiology and protect skin against detrimental radiations. Nutronco’s supplement is based on the highest quality whey protein. Our whey isolate is Non-GMO, identity preserved and purified by a proprietary ion exchange method to the highest level. It has a DIAAS value of 110, meaning it provides 110 % of the amino acid requirements specified by the FAO/WHO. It is carbohydrate free, fat free and rich in branched chain amino acids with the highest leucine content of any known protein necessary for muscle protein synthesis.

 

Peter Acs, MD, PhD – Medical Oncologist

Updated 11:00 AM ET, Friday June 22, 2018

Breast cancer and Muscle mass

Breast Cancer Survival is Linked to Muscle Mass

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In a recent study, scientists found that breast cancer patients with decreased muscle mass may have a significantly higher risk of death compared to patients without it. This study, titled “Association of Muscle and Adiposity Measured by Computed Tomography with Survival in Patients With Nonmetastatic Breast Cancer” was published in JAMA Oncology on April 5, 2018*. They examined 3,241 women from Kaiser Permanente of Northern California and Dana Farber Cancer Institute of Harvard Medical School between January 2000 and December 2013. Very importantly, these patients did not have metastatic cancer but rather were diagnosed with stage II or stage III breast cancer that are potentially curable. According to their results, muscle characteristics appear to be important predictors of survival for those who have breast cancer. Patients who had decreased muscle mass were 41 percent less likely to have survived than those who did not. Patients with the highest amount of body fat were also linked to an increased mortality risk. Patients who had both were 89 percent more likely to have died. At Nutronco we have been emphasizing the utmost importance of nutrition and especially protein intake to help rebuild and maintain muscle mass in cancer patients. This is the largest study to date of patients with nonmetastatic breast cancer, and it demonstrated that decreased muscle mass (sarcopenia) is underrecognized, highly prevalent, and is associated with a significant increased risk of death. The authors of the study concluded that we should consider interventions to improve muscle mass such as protein supplementation. Our PowerOnco supplement provides high quality pure protein with high amount of branched chain amino acids, especially leucine, that has been shown to be the most powerful booster of muscle mass.

*Caan BJ, Cespedes Feliciano EM, Prado CM et al.  Association of Muscle and Adiposity Measured by Computed Tomography with Survival in Patients With Nonmetastatic Breast Cancer. JAMA Oncol 2018 Apr 5.

 

Peter Acs, MD, PhD – Medical Oncologist

Updated 7:00 PM ET, Thursday June 21, 2018

Tumor Grade Cancer

What Is Cancer?

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Cancer develops when cells start growing without control and spread into surrounding tissues. This can happen in any type of cell in any organ. Cells normally grow and divide to form new cells as the body needs them, and when cells become old or damaged they die. In cancer cells this mechanism gets impaired and cells continue to grow even when they should die or when they are damaged. The resultant tumor becomes malignant, and called cancer, when these abnormal cells start to grow into surrounding tissue. Eventually, some cells will acquire the ability to travel to distant places in the body and form new tumors at these locations.  Once a cancer diagnosis is made the extent of the disease must be assessed. This is called staging. Typically stage I cancers are small and localized, stage II ones are larger but still localized. Stage III cancer has moved to lymph nodes, whereas stage IV disease means disease in distant organs. This is called metastatic cancer. Staging determines treatment options. Stage I cancer is usually curable with surgery, while the treatment of choice for stage IV cancer is systemic chemotherapy.

Peter Acs, MD, PhD – Medical Oncologist

Updated 4:30 PM ET, Monday April 23, 2018

Tree of Life

Nutronco is launching a fund that will help donate these groundbreaking nutritive products to chemotherapy patients in need. 50 to 80% of chemotherapy patients have nutritional issues according to the National Cancer Institute. Your support is crucial to the success of our mission. Make a small donation, and help make a big difference in a patient’s life. In addition to donating these vital products to someone in need, you will also help us build a company that will continue to develop and revolutionize how nutrition benefits people fighting for their health.

Tumor Grade Cancer

What Is Cancer Cachexia?

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Cancer cachexia is a multifactorial condition characterized by systemic inflammation and severe wasting of skeletal muscle, with or without wasting of adipose tissue (fat). It causes considerable morbidity and mortality in these patients. Cachexia occurs in 50–80% of cancer patients and it has been identified as an independent predictor of treatment failure and decreased survival. There are several factors that contribute to nutritional deterioration, muscle wasting and worsening weight loss in cancer patients. The process is a vicious cycle caused by weakening of the immune system, further inflammation, infection, worsening weakness, widespread metabolic changes, debilitation which collectively contribute to an increase in fatigue, poor physical function, diminished quality of life and ultimately death. Improving nutrition, rebuilding muscle mass and strength, supporting the immune system, decreasing inflammation help prevent this from happening and enables us to treat the underlying malignancy more effectively.

Peter Acs, MD, PhD – Medical Oncologist

Updated 11:00 AM ET, Tues April 17, 2018

Tumor Grade

Cancer and Xylitol

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Xylitol is a natural sugar alcohol that can be used as a food sweetener. It is permissible for cancer patients since it is not fermented by cancer like glucose, and a significantly smaller percentage is absorbed in the GI tract. Xylitol even reduces intestinal glucose absorption. Furthermore, xylitol can alleviate treatment side effects like dry mouth and mucositis. It also has antimicrobial properties especially against encapsulated organisms like Pneumococcus, and was shown to have anticancer effects in lung cancer cells. A study of lung cancer cell lines demonstrated that xylitol has a dose-dependent inhibitory effect on cell proliferation. A different study also demonstrated that xylitol has an antiproliferative effect in vitro. In this study, normal cells and oral squamous cell cancer cell lines were treated with glucose or partial substitution of glucose with xylitol. Partial substitution of glucose with xylitol resulted in decreased cell proliferation. A metabolite of xylitol, D-xylulose, further enhanced the antiproliferative activity of xylitol. In addition, there are no data to suggest that xylitol is carcinogenic or is associated with an increased risk of cancer.

Peter Acs, MD, PhD – Medical Oncologist

Updated 1:30 PM ET, Mon April 9, 2018

What Is Tumor Grade

Immune Benefits of Nucleotide Supplements

There are many health benefits to taking a nucleotide supplement, but the boost to the immune system is probably the best-documented effect. The evidence is very strong that taking nucleotide supplements strengthens the immune system. In fact, nucleotides are necessary for a healthy immune system. They support normal T-cell development, increase the activation of T lymphocytes, increase the number of Natural Killer cells, enhance polymorphonuclear phagocytosis and increase circulating levels of IgG, IgM and interferon gamma. Studies show that dietary nucleotides are necessary for optimal levels of antibodies, both in the serum and in saliva. All these add up to an enhanced resistance to cold and flu infections as well as a better ability to resist more serious microbes. Nucleotide supplementation is an important component of immunonutrition. Along with L-arginine and fatty acids, nucleotides boost the immune system in patients with various conditions resulting in shorter hospital stay, improved wound healing and decreased infections. Dietary nucleotides also improve markers of immune response to strenuous exercise and help gut mucosal defense.

Peter Acs, MD, PhD – Medical Oncologist

Updated 9:42 AM ET, Mon April 2, 2018

Cancer and Sugar

Cancer and Sugar

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According to several research studies cancer cells are metabolically different from normal cells. It was initially suggested over 60 years ago, by Noble laureate Otto Warburg, that the most prominent feature of tumor cell metabolism (the so-called Warburg effect) is the cancer cells’ strong dependence on sugar. Warburg proposed that cellular respiration must be irreversibly injured in cancer cells. Although the concept has been refined, aerobic glycolysis (use of sugar for energy) is still considered to be a hallmark of cancer. This opens up novel therapeutic strategies exploiting this potential Achilles heel of cancer. This so-called “ketogenic diet”, that is high in fat and low in carbohydrates, is considered to have beneficial effects by forcing cells to utilize fatty acids as their primary energy source. There is increasing amount of evidence implying that the ketogenic diet is an effective adjuvant cancer therapy. Most cancer cells lack the enzymes necessary to metabolize fat or protein and they depend on sugar. Sugar does not cause cancer, but if we restrict carbohydrates, the main source of glucose, we make it difficult for cancer cells to divide and they may starve to death. Recently, a group of scientists in Belgium found a direct link between sugar intake and cancer. Besides providing a clear warning to cancer patients to reduce sugar consumption, they identified a mechanism by which high sugar activates the aggressiveness of cancer. According to the lead author, there are some recent clinical trials which indicate that low sugar diet is beneficial for recovery of patients with cancer especially for those that undergo chemotherapy.

Peter Acs, MD, PhD – Medical Oncologist

Updated 7:00 PM ET, Mon March 26, 2018